You activate Spells and Signets 37% faster. (No effect for non-Mesmer skills with a cast time less than 2 seconds.) In PvE, the recharge time of your Mesmer Spells is reduced by 30%.
FactionsMesmer. Domination Magic 11ComplicateSpellIf target foe is using a skill, that skill is interrupted and disabled for target foe and all foes in the area for an additional 10 seconds.100.220
CoreMesmer. Domination Magic 11DiversionHex SpellFor 6 seconds, the next time target foe uses a skill, that skill takes an additional 44 seconds to recharge.101.912
PropheciesMesmer. Domination Magic 11ShameHex SpellFor 6 seconds, the next time target foe casts a Spell that targets an ally, the Spell fails and you steal up to 12 Energy from that foe.101.330
CoreMesmer. Domination Magic 11Shatter EnchantmentSpellRemove an Enchantment from target foe. If an Enchantment is removed, that foe takes 77 damage.100.620
CoreMesmer. Inspiration Magic 9Drain EnchantmentSpellRemove an Enchantment from target foe. If an Enchantment is removed, you gain 13 Energy and 88 Health.51.320
Variable skill slots (pick one from each category)
Elite skill choices
Pain of DisenchantmentNightfallNecromancer. Curses 10Pain of DisenchantmentElite SpellTarget foe loses 2 enchantments. If an enchantment was lost in this way, that foe and all adjacent foes lose 70 Health.10115 – raise curses to 10.
Shadow ShroudFactionsAssassin. Shadow Arts 9Shadow ShroudElite Hex SpellFor 7 seconds, target foe cannot be the target of enchantments.10120 – raise shadow arts to 9 and domination magic to 11, drop the minor rune of domination magic.
Interruption skill choices
Power DrainCoreMesmer. Inspiration Magic 9Power DrainSpellIf target foe is casting a Spell or Chant, that Skill is interrupted and you gain 19 Energy.5¼20 – if you need more energy.
Cry of FrustrationCoreMesmer. Domination Magic 11Cry of FrustrationSpellIf target foe is using a skill, that foe and all foes in the area are interrupted and suffer 59 damage.10¼15
Power SpikeCoreMesmer. Domination Magic 11Power SpikeSpellIf target foe is casting a Spell or a Chant, that Skill is interrupted and target foe takes 96 damage.5¼12
Utility
Resurrection SignetCoreNo Profession. UnlinkedResurrection SignetSignetResurrect target party member. That party member is returned to life with 100% Health and 25% Energy. This Signet only recharges when you gain a morale boost.3
Energy BurnCoreMesmer. Domination Magic 11Energy BurnSpellTarget foe loses 8 Energy and takes 9 damage for each point of Energy lost. 10220 – provide damage when spiking.
Rune of vitae. (Two if playing Shadow ShroudFactionsAssassin. Shadow Arts 9Shadow ShroudElite Hex SpellFor 7 seconds, target foe cannot be the target of enchantments.10120.)
40/40 curses if playing Pain of DisenchantmentNightfallNecromancer. Curses 10Pain of DisenchantmentElite SpellTarget foe loses 2 enchantments. If an enchantment was lost in this way, that foe and all adjacent foes lose 70 Health.10115, a swift "Don't Think Twice" staff of defense if playing Shadow ShroudFactionsAssassin. Shadow Arts 9Shadow ShroudElite Hex SpellFor 7 seconds, target foe cannot be the target of enchantments.10120.
Strength shield of fortitude, -20% cripple duration.
Strength shields of fortitude, +10 armor against each damage type.
Usage[]
Use your skills defensively, unless your team can make ground by playing aggressively for a moment:
Control hexways by interrupting MigrainePropheciesMesmer. Illusion Magic MigraineElite Hex SpellFor 5..17..21 seconds, target foe suffers -1..7..8 Health degeneration and takes 100% longer to activate skills.10212.
Control hex/condition pressure by interrupting Apply PoisonCoreRanger. Wilderness Survival Apply PoisonPreparationFor 24 seconds, foes struck by your physical attacks become Poisoned for 3..13..16 seconds.15212 and Signet of HumilityCoreMesmer. Inspiration Magic Signet of HumilitySignetTarget foe's elite skill is disabled for 1..13..17 seconds. Your non-Mesmer skills are disabled for 10 Seconds.320.
Against the common earth magic elementalists try to complicate both instances of StoningCoreElementalist. Earth Magic StoningSpellSend out a large stone, striking target foe for 45..93..109 earth damage if it hits. If Stoning hits a foe suffering from Weakness, that foe is knocked down.1515.
Remove attunements from elementalists using Drain EnchantmentCoreMesmer. Inspiration Magic 9Drain EnchantmentSpellRemove an Enchantment from target foe. If an Enchantment is removed, you gain 13 Energy and 88 Health.5220 and Pain of DisenchantmentNightfallNecromancer. Curses 10Pain of DisenchantmentElite SpellTarget foe loses 2 enchantments. If an enchantment was lost in this way, that foe and all adjacent foes lose 70 Health.10115.
Assist spikes.
Hex monks with DiversionCoreMesmer. Domination Magic 11DiversionHex SpellFor 6 seconds, the next time target foe uses a skill, that skill takes an additional 44 seconds to recharge.10312 and ShamePropheciesMesmer. Domination Magic 11ShameHex SpellFor 6 seconds, the next time target foe casts a Spell that targets an ally, the Spell fails and you steal up to 12 Energy from that foe.10230.
If you chose Shadow ShroudFactionsAssassin. Shadow Arts 9Shadow ShroudElite Hex SpellFor 7 seconds, target foe cannot be the target of enchantments.10120 as elite skill, focus the fuse and runner with your other hexes and apply the elite hex shortly before the spike.
Use pain of disenchantment or Shatter EnchantmentCoreMesmer. Domination Magic 11Shatter EnchantmentSpellRemove an Enchantment from target foe. If an Enchantment is removed, that foe takes 77 damage.10120 to remove Spirit Bond (PvPFactionsMonk. Protection Prayers Spirit Bond (PvP)Enchantment SpellFor 8 seconds, whenever target ally takes more than 50 damage from the next 10 attacks or Spells, that ally is healed for 30..78..94 Health.10¼5 before or during a spike.
Contribue damage with Energy BurnCoreMesmer. Domination Magic 11Energy BurnSpellTarget foe loses 8 Energy and takes 9 damage for each point of Energy lost. 10220 if you brought it over a resurrection.
Notes[]
Pain of DisenchantmentNightfallNecromancer. Curses 10Pain of DisenchantmentElite SpellTarget foe loses 2 enchantments. If an enchantment was lost in this way, that foe and all adjacent foes lose 70 Health.10115 causes health loss, not damage, and is therefore unaffected by the damage boost from Jack of All Trades.
Pain of Disenchantment – raise curses to 10.
Shadow Shroud – raise shadow arts to 9 and domination magic to 11, drop the minor rune of domination magic.
Power Drain – if you need more energy.
Cry of Frustration 
